I decided to hunt some giant anacondas in jaggedpine forest and got agro from a wolf and took a faction hit for killing the anaconda. It seems the anacondas are on critters of jaggedpine faction, I'm not sure if this change was on purpose or not. I can remember moving from griffons to anacondas while hunting on live without issues, and an anaconda skin is needed for at least one quest i know of and as far as I know critters of jaggedpine is an un-repairable faction.
P.S. Loving the server so far.